As with luciferin, coelenterazine has to be administered by an appropriate route, most often by tail-vein injection.
Furthermore, if generation of a photonic signal is dependent upon the addition of exogenous substrate, this must be administered by an appropriate route.
The genes required for luciferin production have not been completely elucidated and therefore exogenous luciferin must be administered by an appropriate route, most commonly via intraperitoneal injection, a few minutes before imaging.
Ibuprofen was administered by using an appropriate catheter tube.
Individuals who tested positive for HIV were referred to the local treatment facilities administered by AMPATH for appropriate treatment.
It has high reliability and validity and can be reliably administered by interviewers who have appropriate training.
Animals were routinely monitored by veterinarians for all medical and dental conditions, with appropriate treatments administered by specialists.
It can be reliably administered by lay interviewers who have appropriate training.
Betanin (CAS number: 7659-95-2, TCI, Japan) 25 or 100 mg/kg per day as appropriate was administered by intragastric gavage (i.g., distilled water as vehicle) for five consecutive days (for 3 days before and 2 days after paraquat exposure).
Anaphylaxis has been reported after administration of ecallantide and because of this risk, should only be administered by a healthcare professional with appropriate medical support to manage anaphylaxis and HAE [ 34].
