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XR11576 was administered at fixed doses during the study.
As the study medication was administered at fixed doses, a higher dosage per kilogram body weight was prescribed.
A neurocognitive test battery assessing the most reliable findings in adult patients was administered at fixed time points throughout the study to patients and matched controls.
This multicentre, phase III, randomized, double-blind, placebo-controlled, parallel-group study evaluated the efficacy and safety of ATX-101 administered at fixed doses of 1 and 2 mg cm−2.
In case of treatment failure without signs of severe malaria, children will receive Artesunate-Amodiaquine fixed combination (ASAQ Winthrop®, Geneva, Switzerland) orally, which is the second-line treatment in Mali and Niger, administered at fixed hours for 3 days (25 mg AS /67.5 mg AQ under 9 Kg, 50 mg/135 mg between 9 and 18 Kg, 100 mg/270 mg above 18 Kg).
Among trials focusing on clinical outcomes, a single-centre RCT (n = 20) did not demonstrate a difference in survival, renal recovery or ICU stay in patients treated with CVVH vs. CVVHD administered at fixed doses of 1.7 to 2.0 L/hr [ 18].
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Cisplatin was administered at a fixed standard dose of 75 mg m−2.
This analysis investigated whether, and to what degree, CA19-9 decline represented an accurate prognostic test in a group of study patients with advanced pancreatic cancer undergoing treatment with gemcitabine administered at fixed-dose rate (FDR) infusion.
hMG was administered at a fixed-dose of 75 IU per day and the dose of FSH-HP was adjusted according to the patient's individual response.
To study the effect of multiple dosing on drug concentration in blood, researchers often use deterministic models with the assumption that drugs are administered at a fixed dosage, with equal or unequal (fixed) dosing intervals.
The radioactivity in the Capintec was recorded at this time and was used to calculate CO2 fixation (CO2 administered – CO2 not fixed = CO2 fixed).
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