Sentence examples for administered as high from inspiring English sources

It is poorly water soluble drug (10 g/ml) with 40-45% of bioavailability and administered as high doses 600-800 mg/day.

Following induction of stable contractions by OT, barusiban or atosiban were administered as high- or low-dose bolus or infusion [ 16].

In initial studies by Rosenberg and coworkers at the National Cancer Institute in the United States, rIL-2 was administered as high-dose intravenous bolus (i.v.b).v.b

Due to its long effective half-life of four to six hours, TP is commonly administered as high-dose bolus infusion (about 1 mg every four to six hours).

HPV vaccines can be administered as early as nine.

The CV hazard of diclofenac at doses ≥150 mg daily is estimated to be comparable to that of rofecoxib and celecoxib, as well as ibuprofen administered at high doses [ 9, 15].

When 13- cisRA was administered as a high-dose (160 mg m−2 day−1), intermittent regimen in a Children's Cancer Group phase III randomised trial, a significant improvement in 3-year event-free survival (EFS) was observed (Matthay et al, 1999).

Sodium-4-phenylbutyrate is FDA-approved and is well tolerated when administered at high doses as an ammonium scavenger in the treatment of human urea cycle disorders (13).

There was no correlation between AUC and response, suggesting that OSI-7904L may not need to be administered at doses as high as 12 mg m−2.

We repeated this testing and administered 20(OH)dosesses as high as 30 µg/kg to C57BL/6 mice daily for 14 d and found no significant differences in sera Ca2+ levels compared with control mice and no toxicity as determined by serum chemistry and histological analyses of heart, liver, spleen and kidney.

Prior studies for pancreatic cancer treatment involving gene therapy in combination with gemcitabine have administered drug dose as high as 100 mg/kg/week [ 32] but improved efficacy due to intervention of nano-delivery systems has significantly reduced the required dose [ 33- 35].