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However, the 12-step treatment that Patrick Kennedy repeatedly receives for his addiction - the standard one administered around the country - has never been shown to be effective.
In African randomized clinical trials, several short-course (sc) or single-dose (sd) antiretroviral (ARV) regimens administered around the time of delivery (peripartum) have demonstrated a short-term efficacy to prevent mother-to-child transmission (PMTCT) of HIV-1, as estimated at age 6 8 weeks of life [1], [2], [3], [4].
All patients received 4×10 MBq intradermal injections of 99mTc-nanocolloid administered around the biopsy site scar.
The sensitivity analyses (see Supplement) show that the epidemiological impact of vaccination is similar when two vaccine doses are administered around the age of 1 year.
Although JAK inhibition with all three JAK inhibitors showed rapid and strong suppressive effects on articular inflammation and joint destruction when administered around the peak of arthritis, the effects on the symptoms were not complete (Fig. 1a) [ 7, 8].
After tumours had reached to a volume of 100∼200 mm around 14 days (defined as day 1), 200 μl of IO4-Hep, IO4-LMW-Hep or NAC-HCPS (each 10 mg ml−1 of PBS solution) was subcutaneously administered around the tumour daily for another 6 days.
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Furthermore, most vaccines are not administered around birth, but over the first few years of life.
Besides, most vaccines are not administered around birth, but over the first few years of life (Siegrist, 2001).
Consequently, cisplatin should be less toxic to normal tissue if administered around 4 pm when the target organs (such as kidney and bone marrow) are less susceptible to cisplatin-caused damage.
A randomized clinical trial showed that when 5-FU was given as a continuous intravenous infusion, varying the dose administered such that the maximal dose was administered around 04:00 a.m. (referred to as "chronomodulated therapy") patients experienced a 5-fold reduction in the risk of severe mucosal toxicity compared to a constant rate infusion at the same dose [ 1].
These differences may relate to the observed increased neonatal infectious morbidity and mortality as well as the suboptimal immune responses to vaccines administered around birth [1], [2], [8].
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CEO of Professional Science Editing for Scientists @ prosciediting.com