In September last year, they stopped Teva Pharmaceutical from extending its exclusive right to sell the blockbuster multiple sclerosis drug Copaxone, and fend off generic drug manufacturers for years after its original patent expired, simply by patenting the method to administer it in a 40-milligram dose three times a week.
The validation was done jointly using two PET tracers to confirm the independence of the method to the radiopharmaceutical administered.
Moreover, the seven studies were heterogeneous in a number of areas, including technique used to administer helium; concentration of helium administered; severity of illness; dosage of bronchodilator administered; the method used to measure FEV1; and the correction applied to FEV1 to account for the use of He/O2 (without which FEV1 measurement is known to be imprecise).
One trial measured the paramedics' perception of how comfortable they felt when administering each method to each patient (Reades 2011).
These include the cost of administering the method, the cost of any subsequent treatment, and the costs associated with incorrect diagnosis.
The evaluation of the RM has been tested on a group of healthy children and young boys aged 7 to 16 years: no problems in administering the protocol arose and the method appeared to be sufficiently sensitive to differentiate between the motor behaviours of subjects younger and older than 11 years [ 47].
He explained that there is little in the way of reliable stats for drug use or overdose deaths in Costa Rica, because of how surveys are administered and the method for tracking drug deaths.
A tuberculin skin test was administered to all controls, using the Mantoux method to deliver 5 tuberculin units of purified protein derivative (Tubersol; Sanofi Pasteur Inc., Swifwater, PA) intradermally [18] [20].
Regardless of the method used to administer the survey, the investigator attempted to standardize the interview as much as possible.
It is possible that the method used to administer the questionnaires e.g. face to face or over the telephone might have influenced the results; we were unable to look at this in detail due to the small number of included studies.
Administering other methods to acquire necessary information from children, for example, questionnaires or interviews would yield further insights.
