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39 We had originally intended to use the maximum daily dose of 4 g paracetamol, however, chose to administer half this dose due to concerns of liver toxicity.
For example, were a given experimental manipulation to halve the operant responding for alcohol, this could indicate either that the animal now finds the alcohol to be half as rewarding as before, or that it finds it twice as rewarding and therefore only needs to administer half as much for the same perceived effect.
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The usual technique is to administer one-half gram of disulfiram in tablet form daily for a few days; then, under carefully controlled conditions and with medical supervision, the patient is given a small test drink of an alcoholic beverage.
Earlier this week the commission's powerful agriculture department - which administers half the EU's entire budget - was raided as part of the bribery investigation.
Specifically, haloperidol, clozapine and LY 379268 were administered half an hour before ketamine injections in experiment 1 (see Fig. 1).
In the large Phase II trial in Mozambique [8] the pediatric dosage was obtained by administering half of the adult dose (i.e. 0.25 mL of AS02A).
Only clozapine was used in experiment 2 and was injected at the same time point as in experiment 1. Ketamine injections and saline shams were administered half an hour before fear conditioning, as previous observations in our lab showed that half an hour was sufficient for ketamine-induced increases in locomotor activity to subside [61].
We administered half doses twice daily (0700 and 1400 hours), adjusted for morning bw.
41 Accordingly, in the ENGAGE AF-TIMI 48 trial, patients taking these medications were administered half doses of edoxaban.
The prokinetic dose of metoclopramide is 10 mg three or four times a day, administered half an hour before meals and at bedtime.
GH injections were performed twice a day on weekdays with each subcutaneous injection administering half the daily dose (~3μg/g); the first injection was ~9am and the second was ~4pm (~6μg/g/day total GH treatment).
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