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adjuvants
noun
Plural of adjuvant
Exact(51)
John Treanor, professor of medicine at the University of Rochester, says that there are three candidate adjuvants.
European regulators have been more enthusiastic than American ones about allowing adjuvants in flu vaccines.
Another is to add adjuvants, which are catalysts that improve the efficacy of a vaccine and reduce the amount of active ingredient required.A number of companies have been hoping to get such technologies to the market by 2011 or 2012, and some might be able to help with any shortfall should there be a pandemic later this year.
The key is the use of sophisticated "adjuvants", delivery agents that can reduce the amount of precious antigen required even as they greatly enhance its effectiveness.Vaccines used to be seen as low-technology, commodity products that fetched low margins in rich countries and none at all in poor ones.
It has been used widely in vaccines, although not in flu vaccines, so development work is needed.Despite all the promise of adjuvants, some obstacles remain.
It showed that giving all the jabs simultaneously did not affect the safety or efficacy of any of the vaccines and that the malaria vaccine reduced the risk of infection by over 60%.Dr Cohen points to novel adjuvants (ingredients that increase the body's response to vaccines) as one of the reasons why the vaccine works when many earlier versions failed.
Similar(7)
In the near term, the recent US government order for H1N1 pandemic flu vaccine with a novel adjuvant may suggest there is some hope for approval of Glaxo's Cervarix in the second half.
But recent years have seen a revival both of the vaccine industry in general and of the adjuvant side of things in particular.
Rino Rappuoli, the chief scientific officer at Chiron, is one of those working on a way to make vaccines protective at low doses by delivering the injection along with something called an adjuvant.
Alongside the virus are an antigen and an adjuvant, harmless substances that stimulate T-cell production.
A second study in the same journal was conducted in both Tanzania and Kenya, and it shows the vaccine is indeed improved by using a better adjuvant.
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