Sentence examples for adjusts expression from inspiring English sources

This was seen in Lappalainen et al. (2011): non-synonymous, possibly deleterious, coding mutations together with an eQTL which adjusts expression would be an example of positive epistasis.

There is thus a selective advantage to a novel modifier that adjusts expression level in an imprinted and sex-specific way that is, patrigenic expression of the gene when in males and matrigenic expression when in females.

Current strategies include adjusting expression levels of natural ncRNAs and developing synthetic ncRNAs to target specific genes.

The chapter focuses on these human-compatible systems that are currently competing in preclinical studies for optimal performance in adjusting expression of a single therapeutic (model) gene, (e.g., erythropoietin, insulin or human growth hormone).

Many forms of gene therapy will require the ability to modulate the expression of therapeutic genes to maintain expression levels within a therapeutic window or adjust expression levels based on disease progression within the patient [1].

In general, each methylation flux can be regulated by adjusting expression level and/or substrate level.

For the latter we used the FAMT adjusted expression values in the clustering algorithm.

The idea that epigenetic mechanisms can generate similar phenotypic outcomes by adjusting expression of different genes is not new.

Thereby, miRNAs adjust expression of specific transcription factors in a post-transcriptional manner (Shivdasani, 2006; Ambros and Chen, 2007).

Additionally, correlation of expression levels of regulated genes was required to decrease when adjusting expression levels on the corresponding trans-cluster eSNP.

The carefully adjusted expression level of individual components of the pathway is important to optimize flux and to avoid the accumulation of toxic intermediates.