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Our findings can be important in future rational design of DDS for particle adjustment to specific tissues and pathologies.
EEFB on the other hand does only offer a limited amount of configurations to support different application scenarios; a fine grained adjustment to specific demands is not possible using this approach.
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As the modes are defined through their topology, they combine class-invariant properties with within-class variation that allows for adjustments to specific task constraints.
The risk equations allow adjustment to a specific risk profile and thus give more precise risk estimates than general risk models.
Therefore, the use of empirical or hybrid models may need some adjustment to the specific conditions for new exposure scenarios, whereas the mechanistic model approach would be applicable to any situation that considers time-weighted exposures.
A design adjustment according to specific requirements, in order to get a better fit to ill-duct and reduces complications, is possible.
In particular, they assess separately the adjustment to region-specific shocks, to common shocks with asymmetric effects and to national shocks.
It could therefore be argued that further adjustment to deprivation-specific life tables for the higher background mortality among smokers is not necessary.
At the other two loci (TAGA031Z and GATA8H05), Tishkoff et al. had applied size adjustments only to specific alleles, introducing mismatches in a small number of duplicate pairs; we excluded both TAGA031Z and GATA8H05 from our combined data set.
After adjustment to the average specific gravity, the median concentration of urinary arsenic in infant urine from the NHBCS (0.18 μg/L) was 6.5 times lower than 3-month-old Bangladeshi infants (1.2 μg/L) (Fängström et al. 2008).
Adjustments to mimic specific athletes' individual skills are then made by a design team with input from scouts, former players and coaches.
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