Moreover, the observed lower sensitivity of the SNV detection in samples with higher CN may reflect capture-probe saturation and indicates the need for adjustment of sequencing depth and CN.
Furthermore, their applications depend on manual selection of many parameters and fine adjustments of sequence data.
This indicates that adjustments of sequencing protocols are desirable in order to prevent overrepresentation of these microbes in the data at the expense of AT-rich B. fulgida.
Our analysis indicates that adjustments of sequencing protocols are desirable in order to prevent underrepresentation of B. fulgida in the data.
Most programs perform some adjustment of the sequence tags to better represent the original DNA fragment, either by shifting tags in the 3' direction [13], [14], [15] or by extending tags to the estimated length of the original fragments [16], [17], [18], [19], [20], [21], [22], [23].
The homology model of human DPD was generated by manual adjustment of the sequence of the deposited crystal structure of recombinant pig DPD (PDB-ID: 1h7w; Dobritzsch et al. 2001) to that of the human enzyme using WinCoot (Emsley et al. 2010).
The correct adjustment of the sequencing instrument is an important prerequisite for producing high quality sequencing data.
The DLPFC, on the other hand, is thought to be responsible for planning, stepwise implementation and on-line adjustment of behavioral sequences that require retention of preceding steps in working memory [32].
Unfortunately, the adjustment of the DNA sequence according to the consensus sequence had no measurable effects.
A proper adjustment of the deposition sequence and loading of PdNPs (as a shell) over PtNPs (as a core) of the nanocatalyst could eventually enhance its electrocatalytic activity towards FAO in such a way suppressing the CO poisoning pathway.
