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Treatment adjustments were classified into two different categories: 1) Treatment adjustment not necessary (either due to coverage by the empirical therapy or to lacking clinical relevance); 2) Treatment adjustment necessary due to lacking coverage of empirical therapy.
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Then, anticancer medications were classified as 'yes' when adjustment was required, 'no' when adjustment was not necessary, and 'no data' when no data were available in the literature.
Rejection of the null-hypothesis was confirmed, a multiplicity adjustment not considered necessary.
In general, pH or temperature adjustment was not necessary to achieve effective adsorption.
We show that adjustment is not necessary for SEs of the ∆AUC and two versions of the NRI when added predictor variables are significant and normally distributed.
The voriconazole and fluconazole exposures were virtually unchanged; therefore, dose adjustment is not necessary.
Age adjustment was not necessary given the restricted age range of the cohort.
Thus, dose adjustment is not necessary when apremilast is taken with other strong CYP3A4 inhibitors.
Therefore, dosage adjustment is not necessary for patients with renal or hepatic impairment.
This adjustment was not necessary here as only one flexion or extension angle was obtained in each individual subject.
Dosage adjustment is not necessary in patients with mild to moderate hepatic insufficiency, impaired renal function, or the elderly.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com