Inadequate sympathetic adjustments are known to cause maladaptive blood pressure responses [ 21] and may limit the attainment of maximal exercise performance [ 60, 63, 64].
A study of the association between adjustment disorder and CVD could make an important contribution to the literature, as adjustment disorder is known to be a common, yet understudied, diagnosis both in the USA and abroad.
Proper integration of adaptation to light dark cycles and adequate adjustment of metabolism is known to be crucial for health, fitness and sometimes even survival of plants [ 1, 2], mammals [ 3, 4] and fungi [ 5].
While there is good evidence that this is harmful to health, achievement, and socio-emotional adjustment, very little is known about the brain basis that mediates the detrimental effects of poverty.
Peer behaviour plays an important role in the development of social adjustment, though little is known about its genetic architecture.
Nevertheless, it is likely that this practice is even more common in observational studies than in trials [ 7], since adjustment for confounding is known to be an important issue in observational designs.
If the degree of misclassification is known, adjustment may be achieved by sensitivity analysis.
The birth of a preterm infant has been linked with parental distress and adjustment difficulties, yet little is known about the psychosocial factors contributing to this association.
Once the computational cost of the silhouette coefficient and the used similarity threshold setting strategy is known, adjustments can be made to achieve a better balance between runtime and effectiveness.
The current approach is more conservative and can be modified further by incorporation of age-specific adjustment factors if a pharmaceutical is known to be particularly toxic to a certain life stage according to variability in toxicokinetics and toxicodynamics (Daston et al. 2004; Ginsberg et al. 2004).
