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Based on the results of antimicrobial susceptibility with E. durans, 2 g ampicillin I.V. every 24 h + 40 g/dose of gentamicin (0.8 mg/kg/dose) and post-dialysis I.V. (together with adjustment dosing during dialysis usage) were administered upon admission to our hospital.
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Therapy adjustment (dose increase to 3 × 1 mg or dose reduction to 3 × 0.25 mg) occurred basing on blood glucose level measured 2 hours after a meal.
Regular weight-adjustment dosing and strategies to reinforce and maintain ART adherence are essential to maximize duration of first-line therapy in children in resource-limited countries.
Study drug dose adjustment or dose maintenance is guided by safety considerations, in particular changes in serum potassium and renal function, which are monitored at each visit.
To adjust for the effect of dose adjustments, dose-normalized tacrolimus concentrations (concentration/dose, C/D ratios) were calculated for each time point.
This risk increases with subsequent cycles if no adjustment in dose (dose de-escalation) is made.
Importantly, most cases could be effectively managed with dose adjustments, dose delays, and/or myeloid growth factors; 20 % of patients discontinued lenalidomide due to AEs.
Hence, older adults often require renal adjustment of PGB dosing.
Adjustment for dose was performed by adding dose as a time-dependent covariable in the model.
Dose adjustment criteria were based on haematological parameters.
Dose adjustment criteria in non-hematological toxicity in chemotherapy-naïve.
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