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Adjusting the specificity of the DETECT algorithm to recommend similar RHC referral rates (in the DETECT high-risk population) as the ESC/ERS guidelines still substantially reduces the number of missed PAH diagnoses (table 3).
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Primer-BLAST offers flexible options to adjust the specificity threshold and other primer properties.
Any deidentification system will need to be tuned to adjust the specificity of the phrase removal to the desired level.
For example, one may wish to adjust the specificity so that the PPV is constant as a function of the day of the week, season, and trend.
It is possible that patients with clinical disease other than LB may develop cross-reacting antibodies more frequently than the healthy donor population, which was used to adjust the specificity of the IgM antibody ELISA.
We noted that s jj is a factor to find the functionally similar terms in GO tree structure, and d ij is a factor to adjust the specificity of GO modules.
In detail, and, where d i, i=1, 2,…, n, is the GO level of term v i (that is, the longest path length from the root to term v i in the GO hierarchical structure), and α is a parameter to adjust the specificity of GO modules.
The algorithm also allows users to specify options (such as the level of phosphorylation site mismatch tolerance and the maximum length between two entities to be considered) for adjusting the complexity and the specificity of the final prior network.
Consequently, evolution can adjust the affinity, specificity and selectivity of each domain-motif interaction in the network [ 10, 47– 47].
It can provide different degrees of analytical specificity by adjusting the applied potential.
UCHIME reports a score for each sequence, allowing the user to trade sensitivity for specificity by adjusting the minimum score threshold used to discriminate chimeras from biological sequences.
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