Exact(4)
Future studies on the effect, persistence, and virulence of the different CNS species associated with IMI would benefit from using larger and perhaps even shared strain collections and from adjusting study designs to a common framework, as the large variation currently existing therein is a major problem.
(3) The DSMB may also recommend stopping the study, temporarily halting recruitment or adjusting study sites if it seems that recruitment is not proceeding at rates that will allow the study to reach its target sample size in a reasonable timeframe.
The objective of this paper was to extend the Bayesian three-level hierarchical model developed by Prevost et al. [ 5] in order to accommodate the greater potential for bias among the non-randomised studies by adjusting study estimates for potential confounders using differences in patient characteristics between study arms.
Discussions with local partners early on will be invaluable in understanding cultural implications of the proposed study and adjusting study design accordingly.
Similar(56)
Age-adjusted and fully adjusted study results examining (natural logged) ALT and GGT as determinants of incident diabetes were pooled (separately).
Two of the six studies [ 27, 30] did not adjust study estimates for important confounding factors, such as severity of the baseline condition.
Cox regression models were used to estimate adjusted study-specific hazard ratios (HRs), which were combined into pooled hazard ratios (pHR) with corresponding 95% confidence intervals (CIs) under random effects models.
The best quality, case-mix adjusted studies demonstrate a 4 5 fold difference in chemotherapy receipt by network [ 38, 46].
Fixed- and random-effect models were fitted to estimate the summary relative risk (RR) based on adjusted study-specific results.
Restricting the analyses to maximally (multivariate-) adjusted studies (13, 14, 59, 60, 64) resulted in an estimate of 1.59 (95% CI: 1.23, 2.07).
We used logistic regression to perform single SNP analyses for each study separately, adjusting for study-specific covariates.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com