Sentence examples for adjusting expression of from inspiring English sources

The chapter focuses on these human-compatible systems that are currently competing in preclinical studies for optimal performance in adjusting expression of a single therapeutic (model) gene, (e.g., erythropoietin, insulin or human growth hormone).

The idea that epigenetic mechanisms can generate similar phenotypic outcomes by adjusting expression of different genes is not new.

Thereby, miRNAs adjust expression of specific transcription factors in a post-transcriptional manner (Shivdasani, 2006; Ambros and Chen, 2007).

Current strategies include adjusting expression levels of natural ncRNAs and developing synthetic ncRNAs to target specific genes.

The carefully adjusted expression level of individual components of the pathway is important to optimize flux and to avoid the accumulation of toxic intermediates.

tra determines almost all aspects of sexual differentiation, with the exception of the dosage compensation mechanisms that adjust expression levels of X-linked genes (reviewed in [ 3]).

In order to map eQTL adjusted expression values of 1279 unique probe sets showing significant correlation to drip loss were regressed onto the additive and dominance coefficients in intervals of 1 cM using the F2 option of QTL express [ 77].

In order to map eQTL adjusted expression values of 11,457 probe-sets were regressed onto the additive and dominance coefficients in intervals of 1 cM using the F2 option of QTL express [ 29].

This was seen in Lappalainen et al. (2011): non-synonymous, possibly deleterious, coding mutations together with an eQTL which adjusts expression would be an example of positive epistasis.

In contrast with DNA transfection, one can adjust expression levels by changing the amount of mRNA transfected and the frequency of transfection in mRNA transfection.

In order to survive and grow within the hostile environments of host organisms, Y. pestis must acclimatize to environmental changes and respond quickly by adjusting the expression of stress- and virulence-associated genes.