HRs adjusted for components of the metabolic syndrome and randomization group (first 2 years of the follow-up) or baseline CRP level and randomization group did not yield substantial changes in the effects found.
Similarly, the ALC/AMC ratio at the time of first relapse, early relapse (time to relapse after diagnosis, months < 12) and ASCT or not were independently significant predictors of PFS when adjusted for components of the saaIPI on multivariate analysis (Additional file 3: Table S5).
Separate analyses were performed, adjusting for age, race, and sex and adjusting for components of Framingham Risk Score, which we have termed traditional CV risk factors (age, sex, total cholesterol, high-density lipoprotein (HDL) cholesterol, smoking status, systolic blood pressure and anti-hypertensive use) [ 39], and then additionally for the presence of diabetes.
Engineering properties before irradiation are composition and microstructure dependent, and can be adjusted for different components of the nuclear core accordingly.
Quantitative trait association analysis was performed on each study, adjusted for principal components when necessary.
Based on these results, we adjusted for 14 components, which accounted for 1.0%% of the variance in g, and 0.8%% of the variance in height.
Since this geographical specificity could reflect residual population stratification in samples outside northern Europe, we adjusted for principal components in a subset of individuals not from northern Europe.
The models were adjusted for principal components in order to minimise the effect of population substructure, and the Collaborative Oncological Gene-environment Study (COGS) [ 16] dataset was stratified by study.
We used linear regression, adjusted for principal components and study, to estimate the relationship between age at menarche (years) and rs10235235 genotype (0, 1, 2 rare alleles) and logistic regression adjusted for principal components and study to estimate the association between age at menarche and breast cancer risk.
In order to investigate potential residual confounding by population stratification, we adjusted for principal components derived from IBC CardioChip array 24 in studies with available data (see supplementary methods 2.4 for further details).
The intensity measurements were typically adjusted for these components, i.e., the deisotoped and charge state-reduced EMRTs that were replicated throughout the entire experiment for the analysis at the EMRT cluster level.
