Models accounted for clustering and adjusted for study allocation, baseline meal frequency, and demographic characteristics.
The sample size was not adjusted for this allocation.
These proportions were compared between the groups using a Mantel–Haenszel test adjusted for the allocation factors.
The study stems from a statin trial (14), but we observed no interaction by treatment for leptin's associations with end points of interest, and all analyses were adjusted for treatment allocation.
* each model adjusted for group allocation ("intervention") and for any baseline characteristic (race gender, history of asthma, maternal education, residence city, season, child's atopic status) with p<0.05 upon being entered in a stepwise manner.
Genotype effects were similar in prepubertal, early postmenarcheal, and PCOS subjects, and therefore genotype-phenotype associations are presented for all 85 girls studied as a single group (adjusted for group allocation) to maximize the statistical power.
Regular sunscreen use has been shown to reduce the occurrence of SCC in this study population [ 22, 33], and thus we routinely adjusted for treatment allocation in all analyses.
Risk estimates will be adjusted for cluster allocation via generalized estimating equations using a log link between the binary response variable (binomial family) and the linear predictor, and unstructured correlations between observations.
At 18 weeks follow-up, only 15% of those with SI at baseline also had it at 18 weeks, which is not significantly different to those without SI at baseline (6%, p = 0.075 adjusted for treatment allocation, (see table 1).
Hence, the purpose of this study is to assess the effect of unequal randomization on the statistical properties of TT, DTT and SSD adjusted for unequal allocation ratio (SSDadj) by multiple simulation, and SSD using the formulas used by Pocock [ 16].
