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They did not meet the criteria for an adjusted end point and were excluded.
Women reached their study-end point if they had a histological outcome or an adjusted end point.
Finally, two women had a BMD smear as follow-up outcome (1.6%) and thus no adjusted end point as well.
Women with other (combinations of) repeat-test results were considered as having no adjusted end point and were therefore excluded from the analysis.
One HPV-positive woman, having normal cytology and a negative HPV test, was considered to have ⩽CIN1 as an adjusted end point.
For both HPV-positive and HPV-negative women with BMD, the adjusted end point was defined as ⩽CIN1 when they had normal cytology and a negative HPV result as a repeat test.
Similar(54)
Another handy update to ReelSurfer has made it so that when you're clipping longer videos, you don't have to navigate to the right moment by dragging start and end points — users can now press the "A" and "S" keys on their keyboard to adjust start time by a second or use the "D" and "F" keys to adjust the end point.
We manually reviewed each of the resulting clusters, adjusting the end points to more precisely reflect increasing SNV density, merging closely spaced clusters separated by repeats or other regions where SNVs were unable to be called.
The estimated ratios were similar after adjusting for end point A1C, FBG (SMBG), and FSG (laboratory).
The primary end point, adjusted mean HbA1c reduction with dapagliflozin (−0.52%) compared with glipizide (−0.52%), was statistically noninferior at 52 weeks.
This effect was more pronounced in patients <65 years of age, in whom those in the lowest SES quintile experienced a 50% increased risk of the primary end point (adjusted hazard ratio [HR] 1.51 [95% CI 1.45 1.56]) compared with those in the highest quintile, and weaker among those 65 years of age and older (P ≤ 0.0005 for all SES age-group interactionSES age-group
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com