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Secondly, global regulatory systems can adjust the expression of the pathway gene cluster in response to the general physiological status of the microorganism.
Robust transgene expression in the systemic circulation coupled to the ability to switch off and even adjust the expression level may open the way to safer gene-based delivery of therapeutics.
The ribosome binding sites (RBS) of the genes were mutated to adjust the expression level.
The ability to monitor environmental changes within the host organism and adjust the expression of stress- and virulence-associated genes accordingly is critical for the growth and survival of pathogenic bacteria.
To accomplish this, organisms continuously have to adjust the expression of their genes.
Notably, Arabidopsis plants specifically adjust the expression of genes encoding different catabolic enzymes of amino acids in response to different stresses [ 19].
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Another possible explanation for the correlation between genomic imprinting and retention of gene duplicates is that imprinting may be a way of adjusting the expression levels of duplicated genes when expressed in the endosperm.
Accordingly, we adjusted the expression data matrix using the infiltration index to identify over-expressed transcripts unaccounted for by leukocyte infiltration.
1,25(OH)2D3 showed inhibitory effect on excessive inflammatory biomarkers and adjusted the expression reproductive genes and testicular androgen synthesis.
By developing a correlation for the shadowing exponent from the stochastic simulations and adjusting the expression for the initial collection efficiency, reasonably accurate model predictions could be made once the model parameters from a single experiment were determined.
In order to survive and grow within the hostile environments of host organisms, Y. pestis must acclimatize to environmental changes and respond quickly by adjusting the expression of stress- and virulence-associated genes.
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