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Also added in the new version is the functionality to adjust survival models for covariates.
The next step is to adjust survival times based on the amount of treatment a patient actually receives.
19 The utility used to adjust survival for quality of life ranged from 0 1, with 0 representing death and 1 representing perfect health (Table 5).
In addition, given the potential side effects of adjuvant therapy, the model will also adjust survival estimates for the impact of the disease and its treatments on patient HRQoL.
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The latter facilitates comparison of adjusted mortality across different programmes, and avoids problems that occur when adjusting survival curves for confounders [32].
Also, a Southwest Oncology Group study concluded that, after adjustment for SES, African American patients with breast cancer had worse adjusted survival, despite enrollment on phase III clinical trials with uniform stage, treatment, and follow-up [ 56].
The estimated coefficients are given in an accelerated failure time metric, which adjusts survival functions for the effects of covariates.
p ˜ 2 i or p ˜ 2 j = adjusted survival probability of tree i or j at the end of the growth period.
This accelerates mortality increases in the statistically adjusted survival curves.
Morbidity is incorporated in a single outcome measure which adjusts survival for quality of life [11], [12], [17], [18].
However, adjusting survival traits for birth weight did not result in major differences in the results of association of PrP genotypes with postnatal lamb survival (Figure S2).
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