All results presented have been weighted to adjust for the social class stratification in the original sample.
Fractions of a given subject may thus be allocated to different classes, meaning that analyses correctly adjust for the uncertainty in class membership.
However social class was measured with a four category scale, so may not fully adjust for the range of social classes.
Cochran's test was used to adjust for the effects of ethnic group, social class, age and histological subtype (factors associated with EBV status; Flavell et al, 2000)) on this analysis.
In a stepwise multivariate Cox model considering RPA class, chemotherapy and acute CNS toxicities, only RPA class and acute NT remained statistically associated with the overall survival (HR=1.43; 95% CI=1.2 1.7; P<0.0001) after adjusting for the RPA classes (Table 5).
The output saturation is adjusted for the multi-class classifying problem in the ILRBF-BP algorithm.
Namely, after adjusting for the average grade in the class, an individual will expect to receive lower grades in classes where their peers are stronger.
To adjust for class imbalance, we applied the Synthetic Minority Over-sampling Technique, which generated new examples of the minority class (those with DKD) using the nearest neighbors of these cases and under-sampled the majority class examples (those without DKD) [ 15].
Diuretics, beta-blockers, calcium antagonists, drugs acting on the renin angiotensin system (ACE inhibitors, ATII antagonists) and miscellaneous AHD were analysed separately, adjusted for the other ATC classes.
We adjusted for the effect of social class but not educational level and occupation of mothers in the analysis due to the well known fact that education and occupation determines social class of an individual, and also the fact they were unrelated to birth weight in our analysis.
Within each haplotype, we also estimated the effect in terms of odds ratio of each sole variant in Class I adjusted for the effect of the sole variant in Class II loci versus all the other variants in Class I also adjusted for the effect of the sole variant in Class II loci, by fitting a model including both the sole variant in Class I and the sole variant in Class II.
