Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
Thereby, miRNAs adjust expression of specific transcription factors in a post-transcriptional manner (Shivdasani, 2006; Ambros and Chen, 2007).
Similar(59)
The chapter focuses on these human-compatible systems that are currently competing in preclinical studies for optimal performance in adjusting expression of a single therapeutic (model) gene, (e.g., erythropoietin, insulin or human growth hormone).
The idea that epigenetic mechanisms can generate similar phenotypic outcomes by adjusting expression of different genes is not new.
tra determines almost all aspects of sexual differentiation, with the exception of the dosage compensation mechanisms that adjust expression levels of X-linked genes (reviewed in [ 3]).
In contrast with DNA transfection, one can adjust expression levels by changing the amount of mRNA transfected and the frequency of transfection in mRNA transfection.
The carefully adjusted expression level of individual components of the pathway is important to optimize flux and to avoid the accumulation of toxic intermediates.
Current strategies include adjusting expression levels of natural ncRNAs and developing synthetic ncRNAs to target specific genes.
In order to map eQTL adjusted expression values of 1279 unique probe sets showing significant correlation to drip loss were regressed onto the additive and dominance coefficients in intervals of 1 cM using the F2 option of QTL express [ 77].
In order to map eQTL adjusted expression values of 11,457 probe-sets were regressed onto the additive and dominance coefficients in intervals of 1 cM using the F2 option of QTL express [ 29].
This was seen in Lappalainen et al. (2011): non-synonymous, possibly deleterious, coding mutations together with an eQTL which adjusts expression would be an example of positive epistasis.
Secondly, global regulatory systems can adjust the expression of the pathway gene cluster in response to the general physiological status of the microorganism.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com