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Because over 95% of our samples were unrelated individuals, we did not adjust analysis for family relatedness, but closely monitored evidence of genomic inflation.
The study was not able to consider confounding variables and other risk factors that can be used to adjust analysis such as presence of DMT2, skin color, sun exposure information and season where vitamin D was measured, the latter 2 factors being considered as very important predictors for vitamin D status in this geographical region [ 53].
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n = 144 for estrogen adjusted analysis and n = 143 for covariate adjusted analysis.
If a study reported more than one adjusted analysis, we selected in order of preference (1) the main adjusted analysis mentioned in the abstract, (2) the main adjusted analysis mentioned in the conclusions and (3) the main adjusted analysis mentioned in the results section.
Stratification and minimisation are not alternatives to covariate adjusted analysis; in fact they establish the need for one.
Four of 11 patients in group 2 had complications and 11 of 90 in group 1, adjusted analysis (RR 2.7, 95% CI 0.4 16.2, p = 0.3).
The increased duration of both the first and second stages of labor increased injury risk in the unadjusted, but not adjusted, analysis.
Factors where the likelihood ratio test (LRT) p value was ≤0.1 in minimally adjusted analysis were considered for inclusion in multivariate models.
On adjusted analysis there was an association between trend towards low CD4 count (pt = 0.024), low weight (pt = 0.026) and TB diagnosis.
For example, rs646776 and rs10903129 have previously been associated with lipid levels and coronary heart disease risk, however, the rs10903129 eQTL was missed in the eigenvector adjusted analysis.
**: adjusted analysis.
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