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There are several lines of evidence suggesting that the blood-brain barrier could be a valid adjunctive target for anti-epileptic drug therapy.
Furthermore, SIRT3 may serve as an adjunctive target to improve the efficacy and decrease the side effects of conventional treatments.
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Future studies will help determine the potential use of CHAC1 as an adjunctive therapeutic target for HNSCC.
Assessment of cognitive effects of adjunctive therapies targeting specific cognitive domains or impairments may require more extensive testing of the domains targeted to maximize sensitivity for detecting specific predicted cognitive outcomes.
Interventions in metabolic remodeling therefore represent a promising therapeutic adjunctive for targeting pathological cardiac hypertrophy and development of heart failure (Ardehali et al, 2012).
Peripheral arterial tonometry may have a role as a user-independent method of monitoring responses to novel adjunctive therapies targeting endothelial dysfunction in sepsis.
The discovery of antiretroviral medication that suppresses inflammation in addition to HIV replication or adjunctive therapy targeting uncontrolled inflammation may be important in the prevention of comorbid conditions associated with chronic HIV infection, such as diabetes.
Given the growing interest in HMG CoA reductase inhibitors [ 58] and other potential adjunctive therapies targeting the endothelium in sepsis [ 55], better tools for monitoring the response of the endothelium in clinical trials are needed.
In contrast, adjunctive treatments targeted at specific secondary conditions are typically longer and may unnecessarily postpone decreases in PTSD symptoms and related comorbidity or even increase the risk of dropout before the patient arrives at the trauma-focused treatment phase.
Further understanding the role of androgen receptor-related alpha6beta4 integrin expression in prostate cancer cells responses to freezing might lead to novel options for neo-adjunctive treatments targeting the AR signaling pathway.
Promising adjunctive therapies that target microvascular dysfunction, including platelet glycoprotein IIb/IIIa inhibitors, and agents designed to improve tissue perfusion and attenuate reperfusion injury are being evaluated to further improve clinical outcomes after acute MI.
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CEO of Professional Science Editing for Scientists @ prosciediting.com