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36 The JECS allows additional investigations, or adjunct studies, pertaining to the main study.
The NCS also offers major opportunities to study the validity and reliability of alterative measurement approaches through adjunct studies in collaboration with existing study centers.
A repository of bone marrow and blood samples will be very valuable also for future adjunct studies involving immunohistochemistry, FISH and molecular techniques.
However, we would point out that the method is designed to facilitate broad qualitative judgments in adjunct studies or be used in contexts where limited quantitative data are available, not act as a substitute for traditional quantitative analyses.
The NCS provides opportunities for related investigations by affiliated and nonaffiliated investigators through adjunct studies conducted at NCS study locations or through analysis of data collected in the NCS to address a wide range of additional questions beyond the core study hypotheses.
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This 4-year birth cohort study began in 2011 as an adjunct study of the Japan Environment & Children's Study (JECS) involving three regions: Kyoto, Toyama and Tottori.
At first the camera was seen as a tool that could replace the artist's hand, but over time the camera's unique capacities its instantaneousness and ability to see more than the human eye (and with better focus)—clearly set a photograph apart from a painting and made photography not an adjunct study but rather a distinct medium valuable in and of itself.
JECS participants in the three regions who also agreed to participate in this adjunct study were enrolled before delivery.
32 Withdrawal rates from the EASE-PD Adjunct study were comparable between ropinirole prolonged release and placebo, with 5% of each group withdrawing from the study.
'Effects of desert dust exposure on children's health' is our adjunct study involving three JECS regional centres in Kyoto, Toyama and Tottori (figure 1).
Another adjunct study of IMPACT, IMPACT-genes and hormones, will collect salivary cortisol pre- and post-therapy to assess HPA-axis functioning [ 30].
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