The phrase "adjudication of trial" is not correct and may cause confusion in written English.
It is typically used in legal contexts to refer to the process of resolving a dispute or making a judgment in a trial setting, but the phrase itself is redundant.
Example: "The adjudication of trial was lengthy, but the verdict was finally reached."
Alternatives: "trial adjudication" or "judicial determination".
Furthermore, the FIRST trial has methodological safeguards including the use of a centralized system to randomize patients; blinding patients, outcome assessors, data analysts, and the Steering Committee; standardization and documentation of peri-operative care; the use of strategies to limit loss to follow up; and adjudication of trial events by an independent Adjudication Committee.
The study has stringent methodological safeguards against bias including: use of a centralised randomisation system; blinding data analysts and the Steering Committee; standardisation and documentation; use of strategies to limit loss to follow-up; and adjudication of trial events by an independent Central Adjudication Committee.
Central Adjudication (of cases), Trial Oversight and Safety Committees will monitor trial conduct.
The goals of such litigation often vary, but by using a mass torts approach, plaintiffs and defendants alike are typically able to produce meaningful relief to victims and bring about financial peace for defendants, without resorting to unpredictable, costly and time-consuming adjudication by trial of every individual claim.
See web extra appendix 2 for more detailed description of external adjudication of events in individual trials.
LIMITATIONS: It is difficult to document the value of adjudication in trials that have reported adjudicated and nonadjudicated event rates and related treatment effects.
Fifty six trials (56%) reported blind adjudication of clinical outcomes, and for 69 trials (69%) we were able to include all randomised patients into the analysis according to the intention to treat principle.
An ancient form of adjudication known as trial by ordeal became commonplace after 500 A.D.; its heyday lasted from 800 to 1200 A.D. In trial by ordeal, a defendant submits to a gruelling physical test, the outcome of which is taken as a sign from God, an indication of guilt or innocence.
In the linagliptin clinical trial program, adjudication of hospitalization for CHF was implemented during phase 3b.
23 Strengths of this protocol and the overall SIRS trial are generalisable estimates derived from patients recruited in 81 centres in 18 countries and rigorous randomised trial methodology (eg, concealed allocation, placebo-controlled trial, blinded central adjudication of the outcomes).
Strengths of this POISE-2 AKI protocol and the overall POISE-2 trial are generalisable estimates derived from patients recruited in an international context using rigorous randomised trial methodology (eg, concealed allocation, placebo-controlled trial, blinded central adjudication of outcomes).
