The phrase "adjudication end" is not correct and does not convey a clear meaning in written English.
It seems to refer to the conclusion of a legal process or decision-making, but it lacks clarity and context.
Example: "The adjudication end of the case was marked by the judge's final ruling."
Alternatives: "conclusion of adjudication" or "end of the adjudication process".
Additionally, an independent clinical event committee (CEC) prospectively reviewed, in a blinded fashion, all reports of treatment-emergent fatal events and suspected cardiovascular (CV) events and evaluated whether prespecified criteria for adjudication end points (CV death, stroke, MI, and hospitalization for unstable angina) were met.
These trials, however, have varied regarding patient population, type, duration and timing of IIb/IIIa therapy, adjunct therapies, and methods for collection and adjudication of end points.
Adjudication of end points was performed by central committees comprised of experts in each complication based on additional data such as those obtained by computed tomography or magnetic resonance imaging of the brain or sequential changes in electrocardiograms.
Fourthly, only a minority of trials was randomised or prospective and a blinded analysis and/or central adjudication of end points was performed in none (ie, the higher level of data quality).
The adjudication of end points was performed by central committees comprised of experts who were masked to risk factor status and was based on additional data such as a detailed history, sequential changes in electrocardiogram and serum cardiac biomarkers, and results of coronary angiography.
There will not be adjudication of clinical end points by personnel blinded to exposure and there will be some misclassification of clinical outcomes.
For RegARd-C, there is no end point adjudication committee or steering committee.
They were judged by an independent adjudication committee at the end of the study.
Primary outcomes and all deaths were reviewed and validated by an independent end point adjudication committee blinded to treatment allocation (4, 8).
All outcomes were determined by the members of a separate central end point adjudication committee who used standard definitions and were unaware of treatment allocation and NAT2 genotypes.
Observational studies reflect clinical practice and without end point adjudication, site monitoring, etc., a margin for error must be taken into account.
