Being ordinal, the unit difference between adjacent scores is not equal at different levels of the score domain.
Half scores were also allowed, or derived if two adjacent scores were given, and included in the analysis.
In edit-distance scoring, adjacent scores can differ by at most one, and the binary representation stores the locations of (two of the three) possible differences, +1, −1 and zero.
The BitPAl method uses structural properties in the relationship between adjacent scores in the scoring matrix to construct classes of efficient algorithms, each designed for a particular set of weights.
Our contribution is based on an observation of the regularity in the relationship between adjacent scores in the scoring matrix (Section 2.1) and the design of an efficient series of bit operations to exploit that regularity (Section 3).
Rasch Models specify a number of criteria, which if fulfilled result in interval scales where adjacent scores along the scale are equally spaced, a feature which is particularly important for interpreting clinically meaningful differences [ 13].
For analysis of our supporting end point, NIHSS, we grouped adjacent scores into the following categories: 0 (no measurable deficit), 1 4, 5 8, 9 12, 13 16, 17 20, 21 24, and ≥25 (most severe neurological deficit) or death.
Received participant texts were matched to the text they were responding to, and text content was validated to arrive at a single score for each responding patient between 1 and 9, allowing half scores if patients submitted these or two adjacent scores.
The pattern of scoring for adjacent pain score values was not closely clustered.
The criterion of the sum of adjacent LOD scores was used for rippling after ordering each marker sequence.
Gene Ontology analysis was performed on four lists of significantly differentially expressed genes from the comparisons of two adjacent necrosis scores which met the Bonferroni 0.05 threshold.
