Sentence examples for adjacent regulation from inspiring English sources

2.B C, low regulon-size class), neighbor regulation is a stronger determinant (TFs with adjacent regulation: F = 0.70; TFs without: F = 0.29, p<0.01, Wilcoxon rank sum test).

Although the LTRs can be transcribed themselves, the most highly transcribed TEs do not have the largest effects on adjacent regulation of coding genes, suggesting they function predominantly as enhancers.

In contrast when tumor expression is compared to adjacent normals, up-regulation of majority of these processes, except protein metabolism, is not detected.

The phenomena of adjacent gene co-regulation is widespread across eukaryotes, evolutionarily conserved, and functionally significant for maintaining coordinated levels of gene expression.

While further analysis of the cis and trans factors that mediate adjacent gene co-regulation will be required to elucidate how it is achieved, at least three, non-exclusive mechanisms can be proposed: 1) localized chromatin modification, 2) local DNA sequence looping, 3) co-localization of the genes to a common nuclear compartment.

Finally, it is possible that adjacent gene co-regulation may be mediated, in part, at the level of sub-nuclear compartmentalization. High resolution mapping of gene localizations in yeast revealed that transcriptionally active sets of genes, including those involved in ribosome biogenesis, occupied specific nuclear territories at the nucleolar periphery upon activation [ 43].

Thus, we could find no evidence for a consistent pattern of telomere-related silencing or regulation of adjacent genes.

The very close correspondence of RNA levels of K8 and K18 very likely reflect their coordinate regulation from adjacent locations at the distal end of the type II keratin locus on chromosome 12.

Among the most prominent examples are effects on the regulation of adjacent genes.

3 A single DtxR binding site is involved most likely in regulation of adjacent coding regions located on the opposite DNA strand [14, 15].

Adjacent to plasmid inherent regulation mechanisms, the current metabolic status of the cells has an exceeding impact on the production of recombinant proteins as well.