Sentence examples for adhesion turnover from inspiring English sources

Proteolysis of focal adhesion components has been proposed to regulate the protein content of adhesive complexes resulting in the control of focal adhesion turnover and cell migration.

Activation of Src can enhance cell movement by promoting focal adhesion turnover.

Cell migration and hence durotaxis depend on very tightly coordinated processes of focal adhesion turnover and detachment of the adherent rear edge via myosin-II mediated contractile forces.

Hall, C. L., Wang, C., Lange, L. A. & Turley, E. A. Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity.

HDAC6 inhibition yielded a decrease in microtubule dynamics that was sufficient to decrease focal adhesion turnover.

For efficient cell migration, cells must concurrently control both transmission of large forces through adhesion structures and translocation of the cell body via adhesion turnover.

Formation of adhesions proceeded normally and cell spreading was more rapid in the absence of active HDAC6; however, photobleaching assays and adhesion breakdown showed that adhesion turnover was slower.

To test the role of hyperacetylated tubulin in altering adhesion turnover, we measured microtubule dynamics in HDAC6-inhibited cells because dynamic microtubules are required to target adhesions for turnover.

FAK is reportedly necessary for normal focal adhesion turnover and mechanosensing [17], [36].

PF-228 inhibits cell migration concomitant with the inhibition of focal adhesion turnover [38].

Because of its association with the microtubule and the requirement for this structure in the process of focal adhesion turnover, we investigated the role of SLK in microtubule-dependent adhesion turnover.