Sentence examples for adhesion facilitating from inspiring English sources

Through its interaction with the integrin-binding non-receptor tyrosine kinase Fak, and the recruitment of cytoskeletal proteins such as paxillin, Src activity promotes cytoskeletal re-organisation, disruption of cell cell adhesion and modulation of cell matrix adhesion, facilitating epithelial-mesenchymal transition (EMT) and a motile cell phenotype (Frame, 2002).

The integrin-mediated cell adhesion facilitated by these macromolecules provides for cell attachment, spreading, actin organization, and focal adhesion.

To extend the E-selectin/ICAM-1 combined surface study in the context of cell adhesion facilitated by uMUC1, we first utilize the ZR-75-1 and T47D cell lines, which both have been shown to express high levels of uMUC1, to further characterize the differential adhesion of uMUC1 to E-selectin coated surfaces.

In MDCKII cells in response to HGF, HUWE1 catalyzes TIAM1 ubiquitylation and degradation predominantly at cell-cell adhesions, facilitating junction disassembly, migration, and invasion.

The observed changes in both the actin cytoskeleton and focal adhesions facilitate the spreading of post-mitotic cells.

Although leukocytes employ two distinct adhesion molecules that mediate different states of adhesion, the fundamental biophysical mechanisms by which two pairs of adhesion molecules facilitate cell adhesion is not well understood.

This strong inflammatory response is crucially relevant to define the impact of TS at the cerebrovascular level since vascular adhesion molecules facilitate the adhesion of monocyte to ECs and extravasation across the BBB [ 47].

Several adhesion factors facilitating binding to mucosal and epithelial surfaces have been reported [ 2].

Although CD44 expression seems to be correlated with mesenchymal marker expression as well as with invasiveness, CD44 may be one of the most important adhesion molecules facilitating cell invasion and metastasis [ 51].

RAGE plays a role in monocyte migration and microglial activation [ 43, 44] by altering the expression of adhesion molecules, facilitating monocytic extravasation into the CNS and altering microglial cells from resting to activated states [ 45].

Impaired tumor initiation would be consistent with known roles for podocalyxin and CD34-type proteins in blocking cell adhesion and facilitating chemokine-dependent inflammatory trafficking and hematopoietic stem cell engraftment of the bone marrow niche [ 34- 36].