Exact(53)
Adhesion events (bright pixels) reflect the detection of single adhesins.
All adhesion events in the view window over the 7 min observation were counted.
Such adhesion events usually occur between mechanically compliant and hydrated surfaces.
The central idea of this approach is to mimic ligand and receptor mediated physiological adhesion events at cell surfaces.
Adhesion events are essentially located in the septum region (red line), more specifically on the ring-like structure, suggesting that newly formed peptidoglycan is inserted.
Affinity maps (Fig. 5c, d) recorded on cells with a heparin-modified tip revealed adhesion events (bright pixels) in about half of the locations.
Similar(7)
This is a crucial point because hindering the first step of the adhesion event likely represents the only opportunity to block further biofilm growth and development[3].
In this respect, we can envisage that, although nanostructured Au substrates strongly impact the bacterial adhesion capability, the genes codifying for the biofilm expression[27] seem to be unregulated in the early stage of the adhesion event.
In this work, we aimed at uncovering the molecular mechanisms underlying fimbrial expression as a function of surface-related physical stimuli as well as to understand the molecular bases of bacterium/abiotic substrate interaction at the interface in the early stage of adhesion event.
The ability of Rac to activate PAK is dependent on membrane translocation of Rac, which requires an integrin-dependent adhesion event.
Therefore, we hypothesize that FER may be a key regulator in the adhesion event involving these three proteins and may participate in HCC metastasis.
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