While TVC-specific transcriptional inputs control the expression of cell-matrix adhesion determinants, asymmetric adhesion to the extracellular matrix was previously shown to polarize the founder cells and permit localized TVC induction, and thus Foxf expression51.
The overall adhesion determinants resulting from the differential overall compositions as well as within the LCRs and thereby the charge and hydrophobicity characteristics of the 'misses' might be quite different from those of 'hits', accounting for the inability of one or more classifiers to predict them.
In this study, we hypothesized that mechanical cues and the diffusion of the intracellular signal produced by focal adhesions are determinants of the final cellular alignment.
Although ECs share certain common properties, they show variation in regard to structure, antigenic and cell surface determinants, adhesion molecules, and metabolic functions from organ to organ [ 11].
Shain, K.H. & Dalton, W.S. Cell adhesion is a key determinant in de novo multidrug resistance (MDR): new targets for the prevention of acquired MDR.
Selp controls key events related to leukocyte cell recruitment and this adhesion molecule is a determinant modulator of vascular permeability to bacterial elements [42].
On sub-maximally activated, intact HUVEC shear stress became the prevailing determinant of adhesion.
Bacterial adhesion is an important determinant of colonization and infection, including dental caries.
The pneumococcal pilus has been shown to be an important determinant of adhesion and virulence in mouse models of colonization, pneumonia, and bacteremia.
The TIGR4 pneumococcal strain pilus appears to be an important determinant of adhesion and virulence in C57BL/6 mouse models of pneumococcal colonization, pneumonia, and bacteremia (8).
