The phrase "adhesion checkpoint" is correct and usable in written English.
It can be used in contexts related to biology or cellular processes, particularly when discussing mechanisms that regulate cell adhesion and signaling.
Example: "The research focused on the role of the adhesion checkpoint in preventing the proliferation of cancer cells."
Alternatives: "adhesion control point" or "cell adhesion checkpoint".
The function of integrins as adhesion checkpoints for hormone and growth factor signalling is crucial for maintaining the normal architecture and integrity of mammary tissue [ 5].
Poorly differentiated thyroid carcinomas presented molecular signatures related to cell proliferation, poor prognosis, spindle assembly checkpoint and cell adhesion.
Various factors are critical for centrosome clustering, such as cortical actin, the spindle assembly checkpoint (SAC), cell adhesion and polarity regulators, the Ndc80 microtubule-kinetochore attachment complex, augmin complex members, and microtubule motors (e.g., dynein and HSET).
On the plasma membrane, the system can get locally switched on to assemble an adhesion site by passing through checkpoints that enable additional protein interactions in the integrin adhesome.
We propose that at the plasma membrane the system can get locally switched on to self-assemble adhesion sites by passing through checkpoints that induce additional protein interactions in the integrin adhesome.
We propose that adhesion receptor polarization is a parenchymal immune checkpoint that allows functional epithelium to hamper leukocyte binding.
For example, matrix metalloproteinases may act in transformation by inducing apoptosis in anchorage-dependent cells and/or by modifying cell cycle checkpoints through alterations in cell adhesion.
As a result, Wee1 may be more than a G2 checkpoint nullifier, since it also affects cell adhesion molecules.
A lack of adhesion signaling in anchorage-dependent cells results in a block at the G1/S checkpoint of the cell cycle [19].
The authors suggest that both cell contractility and mechanosensing through focal adhesions are controlled by molecular checkpoints that regulate cell polarization.
