During our laparoscopic niche reconstructions that are performed under hysteroscopic evaluation, we find dense fibrotic adhesions attached at the top of the wedge-shaped niches in the majority of our cases (Fig. 4).
This suggests that periodontal ligament fibroblasts indeed recognized the exposed adhesion motifs attached to each scaffold through the integrin receptors for RGD motif or cell attachment motif of laminin PDSGR.
As previously mentioned, loss or degradation of proteins associated with epithelial homeostasis, cell polarity and cell adhesion, such as E-cadherin, RhoA or Plakophilin 2 is frequently observed in EMT (Figure 1A); some proteins that play key roles in cell-cell adhesion when attached to the membrane, such as β-catenin, are redistributed to the cytoplasm [11, 12, 17].
To analyze for altered adhesion, cells attached to the dish (attached) or floating in the medium (nonadherent) were collected and counted.
When a cell initially encounters cell-adhesive ligands, adhesion receptors attach to key peptide or glycan ligands.
The traumatised abdominal sidewall that the adhesions were attached to was excised completely.
Insects have evolved fibrillar attachment devices based on wet adhesion to attach themselves to a variety of surfaces.
Expression of another important adhesin, Hwp1, is likewise hypha-associated (Staab et al., 1999), strengthening the concept of induced, hypha-associated adhesion, as opposed to the ' ad hoc' non-induced adhesion of attaching yeast cells (Wilson and Hube, 2010; Wächtler et al., 2011).
Here, inspired from nature, we report hydrogel diodes with strong and tunable interfacial adhesion by attaching oppositely charged hydrogels together.
Overall, we showed that it is possible to promote specific cell cell adhesion by attaching protein ligands at the surface of cells.
The resulting wing is just two epithelial cell layers thick, with adhesion proteins attaching the layers together [2].
