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Merck says it was simply adhering to the study's original design, and that the more recent chart reflects data that were not available to analyze in early 2005.
Each site will be monitored to assess progress, and to identify any difficulties in adhering to the study protocol.
Practitioners will be contacted every two weeks to ensure that they are adhering to the study protocol.
However, as the participants in the current study were sedentary 20-min sessions were chosen so as not to deter the participants from adhering to the study.
There seemed to be a trend towards subjects in groups receiving bright light therapy adhering to the study more closely than subjects in the exercise group.
In each participating center, a chief investigator will be appointed to be responsible for the whole clinical process (subject recruitment, intervention, follow-up, and data collection), adhering to the study protocol.
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All patients adhered to the study protocol medications for the prescribed duration.
Further, 13 participants did not adhere to the study protocol, complete the questionnaire, or have the full examination.
Nine patients (seven female, two male, age 57.5 ± 14.3 years) were recruited, all of whom adhered to the study protocol.
The only exclusion criteria were a refusal by a patient to participate in the study or a failure to adhere to the study protocol.
During the study, 28 children (20.3 %) dropped out and the main reasons were family relocation, within or outside the country, and failure to adhere to the study protocol.
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