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The main devices used for adherence supports were mobile phone's alarms (62.2%), followed by an alarm clock (22.7%).
The evidence available regarding aliskiren's effect on outcomes, including blood pressure, tolerability, and adherence, supports its use in patients with mild-to-moderate hypertension.
In our observational study, these typical adherence supports are not in place; thus, our data may reflect real-world lapses in patient behaviour in refilling prescriptions, including partial regimen refills, which would not be observed in clinical trials.
Collaborative efforts of the Regional Health Office, Regional HIV/AIDS prevention coordinating office, adherence counselors and adherence supports were recommended to draw effective and efficient interventions targeting these factors.
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25 If assessment of baseline adherence resulted in a participant being initially non-adherent, adherence support was provided before the start of the second intake period.
Initially non-adherent patients received additional adherence support.
25 However, in case of initially non-adherent patients, the provided adherence support might have increased adherence additionally.
Following recruitment, low adherers were offered an adherence support intervention as part of the adherence substudy [ 75].
In the intervention group, participants (n = 119) received adherence support from trained peer supporters who visited participants' houses biweekly during the first two months, thereafter weekly.
If a participant was initially non-adherent, the pharmacist delivered module 3 (adherence support) to the patient additionally.
Although initially adherent patients did not receive specific adherence support, a consistently high median daily adherence in a majority of these patients was observed.
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