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The primary aim is to assess program feasibility in the four domains of process (e.g., recruitment, retention, and adherence), resources (e.g., communication, staff requirements, and monetary costs), management (e.g., time and accuracy in data collection/entry, and reporting of adverse events) and scientific outcomes (e.g., safety, burden, participant feedback and efficacy/outcomes).
Further, the assessment did not capture comprehensive data on access and use of adherence resources outside of the trial, a construct that is gaining attention in adherence research [ 45].
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Multiple challenges stand against the implementation of HAI reduction plans: poor adherence, insufficient resources, staffing problems, lack of culture change, no impetus to change, and issues related to staff and patient education.
In particular, the assessments here were always completed by nursing staff and items which were regularly missed e.g. medication adherence, material resources, may have been considered as the responsibility of other members of the multidisciplinary team i.e. doctors and social workers.
For instance, differences in storage requirements for refrigeration with risperidone LAI that is not a requirement with other long-acting injectable antipsychotic(s) [ 3], any impacts upon improved adherence, and resources required for following up patients who do not attend their 2-weekly appointments.
After meeting the inclusion criteria, patients will be randomly assigned to one of the three conditions (adherence priming, resource priming, or supportive resource priming).
Thus, understanding medication adherence and resource utilization independently among patients with schizoaffective disorder is important.
5 Pill counts have been found to be an economic and reliable measure of adherence in resource-limited settings.
Achieving high rates of adherence in resource poor settings is a serious challenge and performance needs to be closely monitored.
Because of relatively high rates of side effects and the high cost per treatment (US$18.50) [ 83], quinine + clindamycin may result in poor adherence in resource-poor settings.
To our knowledge, there are no other published randomaised controlled trials (RCTs) of text-messaging interventions designed to improve ART adherence in resource-limited settings.
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