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It was used the statistical program Statgraphics Centurion 16.1.11 and the data submitted to Grubbs tests to assess the occurrence of outliers, Kolmogorov to test the adherence of data Bartlett for homogeneity of variance and analysis of variance.
At most, adherence of data to the criteria constrains the scope for alternative, non-causal explanations.
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22 This procedure (defined calibration) aims to estimate the theoretical adherence of simulated data starting from sets of numerical data.
Nevertheless, to some degree, all these methods rely on the adherence of the data to a specified parametric distribution, such as the Gaussian distribution for the t-statistic methods and the mixed-effects model, or the different forms of prior distributions in the Bayesian context.
"There's a built in philosophy of adherence to data and following the data in those companies," says Harvey.
Feedback of adherence data was identified as one of the most successful methods of improving adherence in a systematic review of adherence trials [ 35].
Although some community based studies have reported fairly high levels of adherence, data on factors influencing adherence to artemether-lumefantrine (AL) treatment schedule remain inadequate.
These categories were generated from the tertiles of the distribution of adherence data.
However, as the study was uncontrolled, it remained unclear whether this improvement was simply the effect of introducing the electronic monitoring system, or whether it was the result of the discussions of adherence data which took place between physician, patient, and pharmacist.
Provision of adherence data to providers may motivate patients to improve adherence and help providers identify adherence barriers.
For instance, secondary analysis of adherence data from the trial of COL-1492, an N-9-based gel, indicated that the product increased the risk of HIV infection in women who used it more than 3.5 times daily and who had a high incidence of lesions with epithelial disruption [ 13].
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