Fourth, before IngMeb, there was medical (adherence) need for field directed therapies with shorter and simpler treatment regimens and less long-term irritation and inflammation [ 31].
Identification and use of specific instruments addressed to evaluate asthma control in the elderly with concomitant comorbidities as well as measurements for improving self-management and adherence are needed for better asthma control in the elderly.
But since medical treatment is an important part of the care and good adherence is needed for a therapeutic effect to be achieved, time for adequate information must be prioritized.
A qualitative case study was performed to identify promising strategies to sustain key outcome variables related to the ERAS programme in terms of adherence, time needed for functional recovery and hospital length of stay (LOS), as achieved immediately after implementation.
Consistently, high levels of adherence are needed for reliable viral suppression (Bangsberg et al., 2000; Paterson et al., 2000) and to prevent drug resistance (Bangsberg et al., 2003; Hecht et al., 1998; Pillay, 2001), disease progression (Bangsberg et al., 2001), and death (Garcia de Olalla et al., 2002; Wood et al., 2003).
For example a 95% adherence rate is needed for optimal therapeutic benefit of protease inhibitors to control HIV [ 94], a 90% adherence rate is required for imatinib in the treatment of chronic myeloid leukemia [ 95] and for many medications the adherence rate needed is unknown.
Multiple measures of adherence were used to estimate adherence behavior, and all suggest adherence is in the range needed for treatment success.
The disruptive effect of non-adherence on asthma treatment implies that solutions are needed for improving adherence.
Also, patients who were on follow-up for ≥12 months were included in the study as adequate time was needed for assessing adherence.
Better measures of both adherence and clinical outcomes are needed for future glaucoma research, but what these might be, remains difficult to establish.
