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According to Yanagihara et al., in order to validate a screening program, attention should be paid to quality controls of the screening method, such as the selection of reagent strips, and the participants should be instructed to strictly adhere to the sampling method [ 6].
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Cross contamination due to paper carryover by the punch is not a problem as paper fibres do not adhere to the sample punch, but 'clean' discs may be punched between samples if required.
As compared to most of the cell microarray methods, where a carpet of cells is laid across the whole array [ 9- 12, 14- 17, 19- 21], the CSMA method provides a simplified protocol for achieving a patterned array layout, where cells only adhere to the sample spots.
Because excluding participants not strictly adhering to the sampling protocol might induce selection bias, alternative approaches allowing to statistically standardize measured concentrations are worth investigating.
Our proposed apaThee-coating technique using thus-coatedand precursor-assisted biomimetic process woulayer useful for the creadheredf apatothecoated Y-TZP ceramicsampleorthopedic and dental applicationso
The powder was adhered to the sample holder by a double-sided copper tape.
In solid tumors, the current 'gold standard' is intratumor polarographic measurement of O2 partial pressures using microsensor techniques that adhere to the systematic random sampling principle.
In addition, individuals in which colonoscopic examination remained incomplete due to insufficient bowel lavage or technical difficulties, who did not adhere to the instructions on FIT sampling (e.g. failed to provide the dates of FIT sampling), or could not provide informed consent, were excluded from analysis.
It can be seen from Figure 4a,b,c that typical triangular cells adhere to the surface of all the samples.
Some samples adhere to the carbon support film, but continuous carbon films contribute additional background scattering and reduce the image contrast.
Interestingly, although testicular samples adhere to the sense strand bias we describe above, examples of intense signals from antisense probes are more prevalent in this tissue.
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