Exact(5)
The term "resistance" derives from a laboratory finding consisting in failure of an antiplatelet agent to adequately block its specific target on the platelet (33).
It is not clear that these agents adequately block the upstream activation of this pathway, as they only block TORC1 complex signalling and permit enhanced activation of AKT by TORC2.
Conceivably, tamoxifen did not adequately block estrogen signaling that undermined ZA (discussed below); alternatively, the critical action of estrogen impairing the ZA anti-tumor effect occurred at a site where tamoxifen functioned as an agonist (for example, bone).
We hypothesised that high-level expression of multiple cytokines, many of which have a role in angiogenesis, overwhelms the ability of sorafenib to adequately block tumour angiogenesis and growth.
However, some broad spectrums are better than others, as some sunscreens do not adequately block UVA.
Similar(55)
Another important concern is that the largest trial analyzed did not assessed the effectiveness of the neuromuscular blockade with train-of-four stimulation, so we cannot be sure that patients were adequately blocked [11].
By adequately blocking ACE, mortality can be reduced by approximately 30% (Garg and Yusuf 1995) in spite of incomplete blockade of angiotensin II production.
Another important concern is that the largest trial analyzed did not assessed the effectiveness of the neuromuscular blockade with train-of-four stimulation, so we cannot be sure that patients were adequately blocked [ 11].
The BP profile and BP reductions observed were similar to those seen in the absence of atropine (results not shown here), which suggests that atropine takes some time before it adequately blocks the muscarinic receptors.
4. Dispense molten paraffin wax into an embedding mould to a depth that covers the tissue block adequately.
He knows he is supposed to be a power runner, but he has also been told to be patient so that he can adequately read the blocking schemes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com