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The adequate substitution of Mn by V0.81Fe0.19 can improve overall electrochemical performances of Co-free high-Mn AB5 alloy.
Adequate substitution of fibrinogen was also recommended, prior to administration of PCC.
A number of authors have shown the importance of using adequate substitution models in order to produce accurate phylogenies.
It has often been shown that some of the problems caused by noise can be overcome with adequate substitution models and also that inadequate models can converge on the wrong tree [e.g. [ 5, 88- 99]].
Thus, adequate substitution of the conditionally essential amino acid glutamine in critically ill patients is strongly recommended by international societies with a grade-A level of evidence [ 2, 3].
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"However, we reverse the district court insofar as it held that it is not possible to craft adequate substitutions".
This was likely due to the recent gene duplication that has not yet accumulated enough substitutions to give adequate statistical power.
In our database, history of angina was the closest substitute for ≥2 anginal episodes within the past 24 h; a sensitivity analysis yielded no change in the overall c-statistic, indicating adequate variable substitution.
In case of sepsis-related myocardial depression leading to low cardiac output despite adequate volume substitution, vasopressor treatment with dobutamine should be instituted (AII) [ 140].
The presence of the following criteria were required for the diagnosis of septic shock: (i) systemic inflammatory response syndrome; (ii) evidence of infection; (iii) organ dysfunction; (iiii) circulatory failure requiring vasopressor therapy with norepinephrine for (> 0.1 μg/kg/min) more than five hours to maintain mean arterial blood pressure above 65 mmHg despite adequate volume substitution.
For example, when it is not possible to realize column work with prefabricated elements, then consider whether in-situ work is adequate as a substitution.
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