Exact(1)
Pelletier advised the recording of total joint replacements after 6 years of follow-up; these data, which would serve as an adequate readout for DMOAD trials, can be easily collected by means of questionnaires.
Similar(59)
In addition, the choice of adequate experimental readouts is critical.
Pre-clinical studies need to investigate conditions present in patients, as performed in our washout experiments, and especially pay attention to the lifetime of the drug-target complex [ 64], as well use adequate and informative readouts [ 65].
Serum/plasma sample volume had to be adequate to obtain a valid readout from the ImmunoCAP Allergen c360 Cetuximab test and to yield an interpretable result for the presence of anti-cetuximab-IgE.
In this study, we demonstrated that the prototype system can be applicable to any shaped POI or multi-POIs simultaneously to be focused, provided that adequate sequences for motion control and pixel readout are designed.
The probe readout was monitored for 2 minutes to ensure adequate contact before fixation.
As the EAA requires adequate numbers of patient neutrophils to provide the respiratory burst for the assay readout, we excluded patients who had an absolute neutropenia of less than 0.1 × 10/cm.
This includes target risk assessment, biomarker evaluation and predictivity grading both for efficacy and toxicity, early human trial design adequate to guide stop/go decisions on grounds of biomarker panels, and biostatistical methods to analyze multiple readout situations and quantify risk projections.
Neither clinical score nor paw swelling correlations showed adequate alignment with the inflammation scores, with the pattern of deviation from linearity providing clear evidence that these readouts grossly overestimate drug efficacy regardless of therapeutic class.
"Timer, digital readout.
"0 Min," read the blinking L.C.D. readout.
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