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In the latter study, the use of nitroglycerin was guided by a clinical problem (no adequate decrease in lactate levels despite optimal balance between oxygen delivery and oxygen demand), whereas in the study by Boerma et al. nitroglycerin also was used in patients with normal microcirculation, decreasing, or even normal lactate levels, etc.
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For assessing the impact of depression and anxiety on the use of five classes of standard prophylactic medications we dichotomized ever-before use, contraindications, adverse effects, use for at least three months, intake of an adequate dose, and decrease in headache frequency by at least 50%% and compared presence in none versus presence in one or more of the drugs.
Adverse effects, duration of prophylactic treatment, intake of an adequate dose and decrease in headache frequency by ≥ 50%% did not differ between patients with and without anxiety and/or depression, but patient numbers in the groups were too small do draw definite conclusions.
In preload responsive patients who, despite increase in CO in response to fluid resuscitation, cannot maintain an adequate perfusion, a decrease in vascular tone should be suspected and vasopressors should be given in addition to fluids.
All nodules suspected of lung metastases were successfully resected with adequate margins, and the decrease in pulmonary function was minimal compared with predicted postoperative forced vital capacity (FVC) and forced expiratory volume (FEV) 1.0 calculated by the numbers of subsegments.
Another possible explanation is that the AUC0– ∞ of BMS-184476 alone is not adequate to describe the decrease in ANC when BMS-184476 is combined with carboplatin.
The combination of excessive training load and lack of adequate recovery can lead to a decrease in sport-specific performance associated with fatigue, termed overtraining syndrome (OTS).
RCA-CVVH with a low concentration citrate solution ensured an adequate filter life and allowed a decrease in transfusion rates.
Cervical screening by cytology with adequate treatment have resulted in a decrease in incidence and mortality of cervical carcinoma (Gustafsson et al, 1997; Vizcaino et al, 2000).
There was no significant change in body weight for either treatment group, but the adequate-dairy group exhibited a significant decrease in fat mass (≈1 kg, P < 0.05).
Insulin can, when used in adequate doses, decrease any level of elevated A1C to, or close to, the therapeutic goal.
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