THFV device would facilitate easily reproducible sampling with the added benefit of onsite cytologic evaluation to confirm the adequacy of specimen for the test to be performed.
To assess adequacy of specimen, one pathologist (MRP) counted the number of portal triads within each noncirrhotic specimen; portal triads were not counted in cirrhotic specimens due to architectural distortion.
In a first stage, we used the Olympus® 2.5 mm forceps (standard-oval without needle; required work channel size: 2.8 mm Ø; Shinjuku, Tokyo, Japan) and in a second stage the Endoflex® 3.4 mm (jumbo-oval without needle; required work channel size: 3.7 mm Ø; Voerde, Germany) in order to obtain larger specimens, optimizing the adequacy of the specimens for functional and biochemical studies.
To assess the adequacy of the specimens, we tested each specimen by PCR for the β-globin gene.
To describe the histopathologic adequacy of cervical specimens after ex vivo excision of the cervical canal with cervical coring.
These findings demonstrate that confocal fluorescence microscopy could be used to assess adequacy of IBC CNB specimens.
9 29 40 Close interaction with histopathology is also important to establish comprehensive information about the adequacy of histopathology specimens, the possibility of malignant features, and establishing whether complete resection after endotherapy can be determined.
Without knowledge of clinical, MR imaging, or quantitative histology findings, each reader reviewed the digitized histology images, subjectively assessed the adequacy of each specimen, and assigned to each specimen a Metavir fibrosis score, F0 F4.
All hematoxylin and eosin-stained slides were reviewed to verify the diagnosis and adequacy of the specimen for analysis.
All biopsies were examined by a single liver histopathologist (S. E. D .. Biopsies were classified according to modified Ishak criteria 14 after assessing the adequacy of the specimen.
