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We defined the adequacy of dose of antidepressant drugs as that specified in the British National Formulary (BNF) (www.bnf.org).org
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The PDD/DDD-ratio is used as an indication of the adequacy of dosing.
The included studies did not provide sufficient information to assess adequacy of dosing frequency, dose and duration of TB treatment.
If the data allowed, we assessed the adequacy of dosing frequency, dosage and duration of TB treatment.
We chose to assess the adequacy of dosing in terms of this 'worst-case scenario', as MIC data are often not initially available to the clinician.
Considering the adequacy of dosing, opioid-presciptions had in 12.5% a PDD/DDD-ratio of 1 and in 69.2% a PDD/DDD-ratio lower than 2/3.
The mean initial intravenous colistin total daily dose was similar between the IV and IV/AER groups with no difference in adequacy of dosing of intravenous colistin between the IV and IV/AER patients (Table 3).
The adequacy of treatment dose, dosing schedule and oral continuation therapy in our survey is reassuring; the latter was probably due to recent in-service training conducted on the management of uncomplicated malaria at the time of treatment policy change in Uganda in 2006.
We describe the first end-to-end dosimetry audit for non-SABR (stereotactic ablative body radiotherapy) lung treatments, measuring dose accumulation in a moving target, and assessing adequacy of target dose coverage.
In recent years, numerous clinical pharmacokinetic and therapeutic drug monitoring programs have been launched to assess the adequacy of drug doses and to model dose response in uncomplicated and severe malaria (18 – 20).
Adequacy of the dose was based on the dosages recommended by the Infectious Diseases Society of America and the individual antifungal package insert.
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