Sentence examples for addressing the functional consequences from inspiring English sources

Fully understanding and characterising the interactions and outcomes of the identified gene expression changes is a huge undertaking and will require additional studies addressing the functional consequences of such changes.

In general, these experiments address the functional consequences of thousands of protein variants in a massively parallel manner using genotype-phenotype linked high-throughput functional screens followed by DNA counting via deep sequencing.

This study therefore addressed the functional consequences of immunological changes induced by stroke in humans.

To address the functional consequences of BRAF V600E mutations in PXA, we assessed MAPK pathway activation by measuring levels of phospho-p44/42 phospho-p44/42by IHC.

In the present report, we have addressed the functional consequences of PTH actions in osteocytes by taking advantage of a fragment of the DMP1 promoter that confers osteocyte-specific expression of transgenes [5], [49], [52], [64].

Moreover, many studies have addressed the functional consequences of amino acid deletion or insertion at various positions along the primary sequence.

To address the functional consequences of this PKM2 Oct4 interaction in glioma spheroids and in NSCs, we investigated the effect of DCA on a number of Oct4 transcriptional targets.

Here, we addressed the functional consequences of TiA in NK cells, and we confirmed that malignant target cells caused apoptosis in activated human NK cells [ 14, 16].

Future studies should address the functional consequences of these changes in lung structure in the DKO mice; they should also identify the cargo whose exocytosis is regulated by Rab27 and the molecular mechanisms by which this occurs.

Such studies have the power to uncover many mutations in focussed screens of interesting candidate genes although they do not in themselves address the functional consequences of detected mutations.

We address the functional consequences of different affinities with which internalization pathways are entered and explain how a switch-like response of CIE may result simply from a saturation effect of the CDE pathway.