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So stay tuned.In the meantime, I think it's worth addressing some points made in a recent Alphaville post by Karl Smith.
I'll try by addressing some points in a sequential series.
However, this aspect is extremely important, as response is in daily clinical use and therefore I would assume, there is a must as a scientific and clinical reviewer addressing some points.
These comments center on the being more explicit about the limits of the work, its interpretation (especially regarding the mutants), and comparison to other studies, providing more information about certain analyses, and addressing some points for clarity of presentation and communication.
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Tetrick wrote a response to that article on Medium, titled "My Response," which addressed some points.
Since most of the nitty-gritty details are hammered out in that review, I won't reiterate them here – instead I'll try to address some points Devin had made.
Abbie Hoffman appears as a commentator in the documentary and addresses some points raised in Davis' speech, stating: "It's rather arrogant of Rennie to say that he has found God and has his Telex number in his wallet".
However, I find that the revised manuscript has not fully addressed some points.
Since acquiring more structural information on Ins(1,3,4,5,6) P 5 is one of the main issues in gaining reliable knowledge of the biological roles of this Ins P 5, it is worth addressing some pressing points associated with the structural data presented here for those biologically relevant Ins(1,3,4,5,6) P 5 species.
Maybe the authors would feel like addressing some of the points below in a revised version of the current paper, or in future analyses.
While the reviewers agreed that experiments addressing some of these points are laborious (but doable) these issues need to be at least discussed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com